- decitabine
-
5-aza-2-deoxycytidine, a cytosine analogue that hypomethylates DNA by inhibiting DNA methyltransferase.
Wikipedia foundation.
Wikipedia foundation.
Decitabine — Systematic (IUPAC) name 4 amino 1 (2 deoxy b D erythro pentofuranosyl) 1,3,5 triazin 2(1H) one Clinical data AHFS/ … Wikipedia
decitabine — de·ci·ta·bine (DAC) (de siґtə bēn″) an S phase specific cytotoxic compound used as an antineoplastic in the treatment of acute leukemia; administered by intravenous infusion … Medical dictionary
decitabine — A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It is a type of antimetabolite. Also called Dacogen … English dictionary of cancer terms
Myelodysplastic syndrome — Classification and external resources ICD 10 D46 ICD 9 238.7 … Wikipedia
Myelodysplasie — Klassifikation nach ICD 10 D46 Myelodysplastische Syndrome … Deutsch Wikipedia
Myelodysplastische Syndrome — Klassifikation nach ICD 10 D46 Myelodysplastische Syndrome … Deutsch Wikipedia
Myelodysplastisches Syndrom — Klassifikation nach ICD 10 D46 Myelodysplastische Syndrome … Deutsch Wikipedia
DNA methylation — Illustration of a DNA molecule that is methylated at the two center cytosines. DNA methylation plays an important role for epigenetic gene regulation in development and disease. DNA methylation is a biochemical process that is important for… … Wikipedia
Demethylating agent — Demethylating agents are compounds that can inhibit methylation, resulting in the expression of the previously hypermethylated silenced genes (see methylation: methylation and cancer for more detail). Cytidine analogs such as 5 azacytidine… … Wikipedia
Azacitidine — Systematic (IUPAC) name 4 amino 1 β D ribofuranosyl 1,3,5 triazin 2(1H) one Clinical data Trade names … Wikipedia