- allosteric
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That binds a compound on an inactive site and thus changes conformation in order to become either active or inactiveSee Also: allostery
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allosteric
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allosteric — [al΄ō ster′ik, al΄ōstir′ik; al΄əster′ik, al΄əstir′ik] adj. of or having to do with a protein with a structure that is altered reversibly by a small molecule so that its original function is modified … English World dictionary
allosteric — Of a binding site in a protein, usually an enzyme. The catalytic function of an enzyme may be modified by interaction with small molecules, not only at the active site, but also at a spatially distinct (allosteric) site of different specificity.… … Dictionary of molecular biology
Allosteric enzyme — Allosteric enzymes are enzymes that change their shape, or conformation, upon binding of a modulator. The word allosteric comes from the Greek allos, other and stereos , shape . An allosteric enzyme is an oligomer whose biological activity is… … Wikipedia
Allosteric serotonin reuptake inhibitor — is a marketing classification invented by the pharmaceutical company Lundbeck for its selective serotonin reuptake inhibitor (SSRI) escitalopram, the S stereoisomer of the SSRI citalopram. It is based on the observation that the R isomer of… … Wikipedia
allosteric effect — allosteric effect. См. аллостерический эффект. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
allosteric effector — allosteric effector. См. аллостерический эффектор. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
allosteric enzyme — allosteric enzyme. См. регуляторный фермент. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Allosteric regulation — In biochemistry, allosteric regulation is the regulation of an enzyme or other protein by binding an effector molecule at the protein s allosteric site (that is, a site other than the protein s active site). Effectors that enhance the protein s… … Wikipedia
allosteric control — Inhibition or activation of an enzyme by a small regulatory molecule that interacts with the enzyme at a site (allosteric site) other than the active site (at which catalytic activity occurs). The interaction changes the shape of the enzyme, thus … Universalium
allosteric activation — increase in enzyme activity by binding of an effector at an allosteric site that causes at the catalytic site either increased binding affinity of the enzyme for the substrate or increased rate of catalytic turnover … Medical dictionary
allosteric inhibition — inhibition of an enzyme by binding of an inhibitor at an allosteric site that causes at the catalytic site either reduced binding affinity of the enzyme for the substrate or decreased rate of catalytic turnover … Medical dictionary
