misfolded
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ERAD — Endoplasmic Reticulum Associated Protein Degradation (ERAD) designates a cellular pathway which targets misfolded proteins of the endoplasmic reticulum for ubiquitination and subsequent degradation by a protein degrading complex, called the… … Wikipedia
Proteasome — Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm.cite journal |author=Peters JM, Franke WW, Kleinschmidt JA |title=Distinct 19 … Wikipedia
Chemical biology — is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems.… … Wikipedia
Protein folding — Protein thermodynamics redirects here. For the thermodynamics of reactions catalyzed by proteins, see Enzyme. Protein before and after folding. Protein folding is the process by which a protein structure assumes its functional shape or… … Wikipedia
Ricin — (pronEng|ˈraɪ sɨn) is a protein toxin that is extracted from the castor bean ( Ricinus communis ).The U.S. Centers for Disease Control (CDC) gives a possible minimum figure of 500 micrograms (about the size of a grain of salt) Fact|date=May 2008… … Wikipedia
Histone deacetylase — Histone deacetylases (HDAC) (EC number 3.5.1) are a class of enzymes that remove acetyl groups from an ε N acetyl lysine amino acid on a histone. Its action is opposite to that of histone acetyltransferase.ubtypesHDAC proteins are found in three… … Wikipedia
Clusterin — Identifiers Symbols CLU; APOJ; CLI; KUB1; MGC24903; SGP 2; SGP2; SP 40; TRPM 2; TRPM2 External IDs … Wikipedia
Protein Misfolding Cyclic Amplification — PMCA redirects here. For the transport protein, see Plasma membrane Ca2+ ATPase. Protein Misfolding Cyclic Amplification (PMCA) is an amplification technique (conceptually like PCR but not involving nucleotides) to multiply misfolded prions. It… … Wikipedia
Pharmacoperone — A pharmacoperone (from pharmacological chaperone ) is a small molecule that enters cells and serves as a molecular scaffolding in order to cause otherwise misfolded mutant proteins to fold and route correctly within the cell.Mutation of proteins… … Wikipedia
Biochemistry of Alzheimer's disease — The biochemistry of Alzheimer s disease (AD), one of the most common causes of adult dementia, is as yet not well understood at the molecular level. It has been identified as a protein misfolding disease due to the accumulation of abnormally… … Wikipedia
