trypanothione

trypanothione
An unusual form of glutathione containing two molecules of glutathione joined by a spermidine (polyamine) linker, found in parasitic protozoa such as leishmania and trypanosomes.

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  • Trypanothione — (Mr = 721.86 g/mol) is an unusual form of glutathione containing two molecules of glutathione joined by a spermidine (polyamine) linker. It is found in parasitic protozoa such as leishmania and trypanosomes. [… …   Wikipedia

  • Trypanothione-disulfide reductase — In enzymology, a trypanothione disulfide reductase (EC number|1.8.1.12) is an enzyme that catalyzes the chemical reaction:trypanothione + NADP+ ightleftharpoons trypanothione disulfide + NADPH + H+Thus, the two substrates of this enzyme are… …   Wikipedia

  • Trypanothione synthase — In enzymology, a trypanothione synthase (EC number|6.3.1.9) is an enzyme that catalyzes the chemical reaction:glutathione + glutathionylspermidine + ATP ightleftharpoons N1,N8 bis(glutathionyl)spermidine + ADP + phosphateThe 3 substrates of this… …   Wikipedia

  • Alan Fairlamb — Alan Hutchison Fairlamb CBE, FRSE, FLS (born 30 April 1947, Newcastle upon Tyne, England) is a Wellcome Trust Principal Research Fellow, Professor of Biochemistry and Head of the Division of Biological Chemistry and Drug Discovery at the… …   Wikipedia

  • Lactoylglutathione lyase — Identifiers EC number 4.4.1.5 CAS number 9033 12 9 …   Wikipedia

  • Antioxidant — Model of the antioxidant metabolite glutathione. The yellow sphere is the redox active sulfur atom that provides antioxidant activity, while the red, blue, white, and dark grey spheres represent oxygen, nitrogen, hydrogen, and carbon atoms,… …   Wikipedia

  • Chagas disease — Classification and external resources …   Wikipedia

  • Enzyme inhibitor — Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. Since blocking an enzyme s activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and… …   Wikipedia

  • Maladie De Chagas — CIM 10 : B57 La trypanosomiase américaine (brésilienne) ou maladie de Chagas est une forme de trypanosomiase (comme la maladie du sommeil), une maladie parasitaire qui sévit dans les régions tropicales d Amérique du Sud et centrale. Elle est… …   Wikipédia en Français

  • Maladie de Chagas — Classification et ressources externes Une maladie de Chagas aigüe avec un signe de Romaña caractéristique. Source: CDC. CIM 10 …   Wikipédia en Français

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