- antimetabolite
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Any substance that competes with, or inhibits the normal metabolic process, often by acting as an analogue of an essential metabolite
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antimetabolite
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antimétabolite — ● antimétabolite nom masculin Chimiothérapie anticancéreuse. ⇒ANTIMÉTABOLITE, subst. masc. MÉD. ,,Substance entravant le métabolisme. En particulier, médicament (...) s opposant à certaines réactions chimiques intracellulaires et par conséquent à … Encyclopédie Universelle
Antimetabolite — sind chemische Verbindungen, die natürlichen Metaboliten in ihrer chemischen Struktur ähneln, aber dessen Stoffwechselweg hemmen (Inhibitor). Ergebnis ist eine Störung der normalen Enzymfunktion in einem Stoffwechselweg oder biologischen Prozess … Deutsch Wikipedia
antimetabolite — [an΄tī mə tab′ə līt΄; an΄tēmə tab′ə līt΄, an΄timə tab′ə līt΄] n. a drug or biochemical that inhibits a metabolic process by competing with a similarly shaped metabolite for a particular enzyme … English World dictionary
antimetabolite — /an tee meuh tab euh luyt , an tuy /, n. 1. Biochem. any substance that interferes with growth of an organism by competing with or substituting for an essential nutrient in an enzymatic process. adj. 2. Pharm. of or pertaining to certain… … Universalium
Antimetabolite — The drug methotrexate (right) is an antimetabolite that interferes with the metabolism of folic acid (left). An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.[1] … Wikipedia
Antimétabolite — Un antimétabolite est une substance chimique qui empêche l utilisation d un métabolite, qui est un autre produit chimique qui fait partie du métabolisme normal. Ces substances sont souvent similaires dans leur structure à celle du métabolite avec … Wikipédia en Français
antimetabolite — antimetabolitas statusas T sritis chemija apibrėžtis Biologiškai aktyvus junginys, inhibuojantis metabolizmo fermentus. atitikmenys: angl. antimetabolite rus. антиметаболит … Chemijos terminų aiškinamasis žodynas
antimetabolite — antimetabolitas statusas T sritis ekologija ir aplinkotyra apibrėžtis Gamtinis ar sintetinis biologiškai aktyvus junginys (pvz., metatreksatas, merkaptopurinas, gemcitabinas), pakeičiantis metabolitus biocheminėse reakcijose, trikdantis medžiagų… … Ekologijos terminų aiškinamasis žodynas
antimetabolite — noun Date: 1945 a substance that replaces or inhibits an organism s utilization of a metabolite … New Collegiate Dictionary
antimetabolite — n. [Gr. anti, against; metabole, change] Any compound that interferes with normal cellular metabolism … Dictionary of invertebrate zoology
antimetabolite — (an tī mē tab o laīt) A compound that blocks metabolic pathway function by competitively inhibiting a key enzyme s use of a metabolite because it closely resembles the normal enzyme substrate … Dictionary of microbiology
