hypomethylation

hypomethylation
a decrease in the epigenetic methylation of cytosine and adenosine residues in DNA
See Also: hypomethylated

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  • hypomethylation — hy·po·meth·yl·a·tion (hi″po meth″əl aґshən) 1. presence of fewer methylated nucleotides in DNA than is usual for that DNA; it may be localized or global, and is related to DNA expression. Hypomethylation of specific regions… …   Medical dictionary

  • Methylation — In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with, to be specific, a methyl group, rather than a larger… …   Wikipedia

  • DNA methylation — Illustration of a DNA molecule that is methylated at the two center cytosines. DNA methylation plays an important role for epigenetic gene regulation in development and disease. DNA methylation is a biochemical process that is important for… …   Wikipedia

  • Combined bisulfite restriction analysis — The first few steps of COBRA, and the molecular changes caused by each step to methylated and unmethylated CpG sites. Combined Bisulfite Restriction Analysis …   Wikipedia

  • Epigenetics — In biology, the term epigenetics refers to changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. These changes may remain through cell divisions for the remainder of the cell s life and may also last… …   Wikipedia

  • CpG site — Cytosine Phospha …   Wikipedia

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  • Ethionine — Chembox new ImageFile = ethionine.png ImageSize = IUPACName = 2 Amino 4 ethylsulfanylbutyric acid OtherNames = S Ethyl L homocysteine Section1 = Chembox Identifiers CASNo = 13073 35 3 PubChem = 25674 SMILES = CCSCC [C@@H] (C(=O)O)N Section2 =… …   Wikipedia

  • Alcohol and cancer — Total recorded alcohol per capita consumption (15+), in litres of pure alcohol.[1] Alcohol is associated with an increased risk of a number of cancers.[2] 3.6% of all cancer cases and 3.5% of cancer deaths worldwide are attributable to consu …   Wikipedia

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