phorbol
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Phorbol — [Kurzwort] das, s, trizyklisches Diterpenalkohol (Summenformel C20H28O6), der verestert im Milchsaft zahlreicher Wolfsmilchgewächse enthalten ist. Die Phorbolester wirken lokal stark reizend und kokarzinogen; sie sind z. B. für die Giftigkeit… … Universal-Lexikon
Phorbol — Chembox new Name = Phorbol ImageFile = Phorbol.png ImageName = Phorbol IUPACName = 1,1a,1b,4,4a,7a,7b,8,9,9a decahydro 4a,7b,9,9a tetrahydroxy 3 (hydroxymethyl) 1,1,6,8 tetramethyl 5H cyclopropa [3,4] benz [1,2 e] azulen 5 one Section1 = Chembox… … Wikipedia
phorbol — /fawr bawl, bol/, n. Biochem. the parent alcohol, C20H28O6, of certain carcinogenic compounds in croton oil. [ < G Phorbol (1927) < Gk phorb(é) forage (see FORB) + G ol OL1] * * * … Universalium
phorbol — The parent alcohol of the cocarcinogens, which are 12,13(9,9a) diesters of p. found in croton oil; the hydrocarbon skeleton is a cyclopropabenzazulene; p. esters mimic 1,2 diacylglycerol as activators of protein kinase C. * * * phor·bol fȯr… … Medical dictionary
Phorbol 12,13-dibutyrate — Other names Phorbol dibutyrate; Phorbol 12,13 dibutanoate … Wikipedia
Phorbol-diester hydrolase — In enzymology, a phorbol diester hydrolase (EC number|3.1.1.51) is an enzyme that catalyzes the chemical reaction:phorbol 12,13 dibutanoate + H2O ightleftharpoons phorbol 13 butanoate + butanoateThus, the two substrates of this enzyme are phorbol … Wikipedia
phorbol esters — Polycyclic compounds isolated from croton oil in which two hydroxyl groups on neighbouring carbon atoms are esterified to fatty acids. The commonest of these derivatives is phorbol myristoyl acetate (PMA). Potent co carcinogens or tumour… … Dictionary of molecular biology
phorbol ester — any of several esters of phorbol that are potent cocarcinogens; they are structurally similar to diacylglycerol and can activate protein kinase C. They are used frequently in research to enhance the induction of mutagenesis or tumors by… … Medical dictionary
phorbol — phor·bol … English syllables
phorbol — ˈfȯrˌbȯl, ˌbōl noun ( s) Etymology: International Scientific Vocabulary phorb (from Greek phorbē pasture, fodder) + ol (I); originally formed in German more at pheophorbide : an alcohol C20H28O … Useful english dictionary
