methanethiosulfonate
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Site-directed spin labeling — is a technique for investigating protein local dynamics using electron spin resonance. The theory of SDSL is based on the specific reaction of spin labels with amino acids. A spin label s built in protein structure can be detected by EPR… … Wikipedia
Chemical modification — In biochemistry, chemical modification is the technique of chemically reacting a protein or nucleic acid with chemical reagents. Chemical modification can have several goals, such as to identify which parts of the molecule are exposed to solvent… … Wikipedia