- superantigen
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An antigen, which has a powerful interaction with T-lymphocytes.
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superantigen
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Superantigen — [ thumb|Figure 1. Schematic of Superantigen stimulation compared to normal antigen presentation and activation [2] .] Superantigens (SAgs) are secreted proteins (exotoxins) that exhibit highly potent lymphocyte transforming (mitogenic) activity… … Wikipedia
Superantigen — Superantigene (SAG) umfassen einen Komplex von Toxinen, deren Verhalten weitab von dem Verhalten konventioneller Antigene liegt. Dennoch haben sie antigene Eigenschaften. SAG bewirken eine Dysregulation des Immunsystems, die immer in gleicher… … Deutsch Wikipedia
superantigen — Antigens, mostly of microbial origin, that activate all T lymphocytes that have a T cell receptor with a particular V b sequence; as a consequence superantigens activate large numbers of T cells. Are presented on MHC Class II but are not… … Dictionary of molecular biology
superantigen — Superantigens are bacterial proteins that stimulate the immune system much more extensively than do normal antigens. They stimulate T cells to proliferate nonspecifically through simultaneous interaction with class II MHC proteins on antigen… … Dictionary of microbiology
superantigen — An antigen that interacts with the T cell receptor in a domain outside the antigen recognition site. This interaction induces the activation of larger numbers of T cells than are induced by antigens that are presented in the antigen recognition… … Medical dictionary
superantigen — su·per·antigen … English syllables
superantigen — /supəˈræntidʒən/ (say soohpuh ranteejuhn) noun any of various powerful antigens which initiate a surge of T cells resulting in acute disease such as toxic shock syndrome, or a chronic inflammation as experienced in rheumatic fever …
superantigen — ˌ noun Etymology: super + antigen : a substance (as an enterotoxin) that acts as an antigen capable of stimulating much larger numbers of T cells than an ordinary antigen … Useful english dictionary
Naptumomab estafenatox — ? Monoclonal antibody Type Fab fragment Source Mouse Target 5T4 Clinical data Pregnancy cat. ? Legal status … Wikipedia
Tumoren: Behandlung — Einige bösartige Tumoren produzieren vermehrt bestimmte Eiweißstoffe (Tumormarker), die im Blut nachgewiesen werden können. Eine erhöhte Konzentration eines dieser Tumormarker kann deshalb auf einen Tumor hindeuten. Allerdings wird ein… … Universal-Lexikon
