Insane
131general paralysis of the insane — a late consequence of syphilitic infection. The symptoms are those of a dementia and spastic weakness of the limbs. Deafness, epilepsy, and dysarthria may occur. The infecting organism can be detected in the brain cells and tests for syphilis in… …
132drove him insane — caused him to go crazy, caused him to go mad, unsettled him, exasperated him …