metyrapone

metyrapone
A drug used in the control of hypercortisolism

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  • Metyrapone — Systematic (IUPAC) name 2 methyl 1,2 di(pyridin 3 yl)propan 1 one Clinical data Trade names Metopirone …   Wikipedia

  • metyrapone — An inhibitor of adrenocortical steroid C 11 β hydroxylation, administered orally or intravenously to determine the ability of the pituitary gland to increase its secretion of corticotropin; because 11 deoxycorticosteroids, as a consequence of m.… …   Medical dictionary

  • metyrapone test — (for Cushing syndrome) plasma 11 deoxycortisol or urinary 17 hydroxycorticosteroids are measured after the administration of metyrapone; levels are increased in patients with Cushing disease but not in patients with ectopic ACTH syndrome …   Medical dictionary

  • metyrapone — me·tyr·a·pone …   English syllables

  • metyrapone — n. a drug that interferes with the production of the hormones cortisol and aldosterone and is used in the diagnosis and treatment of Cushing s syndrome. It is administered by mouth. Side effects may include nausea, vomiting, low blood pressure,… …   The new mediacal dictionary

  • metyrapone — məˈtirəˌpōn noun ( s) Etymology: methyl + rapone (perhaps alteration of propanone) : a metabolic hormone C14H14N2O that inhibits biosynthesis of cortisol and corticosterone and is used to test for normal functioning of the pituitary gland …   Useful english dictionary

  • Метирапон (Metyrapone) — лекарственное вещество, влияющее на выработку в организме человека гормона альдостерона; применяется для лечения синдрома Кушинга. Назначается внутрь. Возможные побочные эффекты: тошнота, рвота, снижение кровяного давления и аллергические реакции …   Медицинские термины

  • МЕТИРАПОН — (metyrapone) лекарственное вещество, влияющее на выработку в организме человека гормона альдостерона; применяется для лечения синдрома Кушинга. Назначается внутрь. Возможные побочные эффекты: тошнота, рвота, снижение кровяного давления и… …   Толковый словарь по медицине

  • Critical illness-related corticosteroid insufficiency — (CIRCI) is a form of adrenal insufficiency in critically ill patients who have blood corticosteroid levels which are inadequate for the severe stress response they experience. Combined with decreased glucocorticoid receptor sensitivity and tissue …   Wikipedia

  • Cyproterone — and its acetate Systematic (IUPAC) name 6 chloro 1β,2β dihydro 17 hydroxy 3′H cyclopropa[1,2]pregna 4,6 diene …   Wikipedia

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