chiral resolution

chiral resolution
A process in stereochemistry to separate racemic compounds into their enantiomers.

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  • Chiral resolution — in stereochemistry is a process for the separation of racemic compounds into their enantiomers.[1] It is an important tool in the production of optically active drugs. Other terms with the same meaning are optical resolution and mechanical… …   Wikipedia

  • Chiral column chromatography — is a variant of column chromatography in which the stationary phase contains a single enantiomer of a chiral compound rather than being achiral. The two enantiomers of the same analyte compound differ in affinity to the single enantiomer… …   Wikipedia

  • Chiral pool synthesis — is a strategy that aims to improve the efficiency of chiral synthesis. It starts the organic synthesis of a complex enantiopure chemical compound from a stock of readily available enantiopure substances. Common chiral starting materials include… …   Wikipedia

  • Resolution — may refer to: Resolution (audio), a measure of digital audio quality Resolution (logic), a rule of inference used for automated theorem proving Resolution (law), a written motion adopted by a deliberative body Resolution (debate), the statement… …   Wikipedia

  • Chiral ligand — In chemistry a chiral ligand is a specially adapted ligand used for asymmetric synthesis. This ligand is an enantiopure organic compound which combines with a metal center by chelation to form an asymmetric catalyst. This catalyst engages in a… …   Wikipedia

  • Chiral auxiliary — A chiral auxiliary is a chemical compound or unit that is temporarily incorporated into an organic synthesis so that it can be carried out asymmetrically with the selective formation of one of two enantiomers[1][2] . Chiral auxiliaries are… …   Wikipedia

  • Chiral derivatizing agent — A chiral derivatizing agent (CDA) also known as a chiral resolving reagent, is a chiral auxiliary which can convert a mixture of enantiomers into diastereomers in order to analyse the quantities of each enantiomer present within the mix. In NMR… …   Wikipedia

  • Chiral Photonics — Chiral Photonics, Inc. is a photonics company based in Pine Brook, New Jersey, founded in 1999. The company is developing a new class of optical devices based on twisting glass optical fibers. These in fiber devices aim to displace discrete… …   Wikipedia

  • Chiral Lewis acid — Chiral Lewis acids (CLAs) are a novel class of Lewis acid catalyst used in enantioselective asymmetric synthesis reactions which produce optically active products from optically inactive or impure starting materials. This type of preferential… …   Wikipedia

  • Kinetic resolution — In kinetic resolution, two enantiomers show different reaction rates in a chemical reaction, thereby creating an excess of the less reactive enantiomer.[1] This excess goes through a maximum and disappears on full completion of the reaction.… …   Wikipedia

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