- proton pump
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Any protein in the membrane of a cell or mitochondrion whose function is to move protons across the membrane and thus establish an electrochemical potential.
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proton pump
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proton pump — n a molecular mechanism that transports hydrogen ions across cell membranes * * * the enzyme in the oxyntic cells of the stomach that causes acid secretion by producing hydrogen ions in exchange for potassium ions. * * * a system for transporting … Medical dictionary
Proton pump — This article is about proton pumps in general. For the proton P type ATPase, see proton ATPase. A proton pump is an integral membrane protein that is capable of moving protons across the membrane of a cell, mitochondrion, or other subcellular… … Wikipedia
Proton pump inhibitor — Proton pump inhibitors (or PPI s) are a group of drugs whose main action is pronounced and long lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available today. The group followed and has… … Wikipedia
proton pump inhibitor — n any of a group of drugs (as omeprazole) that inhibit the activity of proton pumps and are used to inhibit gastric acid secretion in the treatment of ulcers and gastroesophageal reflux disease abbr. PPI * * * (PPI) an agent that inhibits the… … Medical dictionary
proton pump inhibitor — noun Any of several short term treatments for gastric and duodenal ulcers and for the eradication of the bacterium helicobacter pylori (abbrev PPI) • • • Main Entry: ↑proton … Useful english dictionary
proton-pump inhibitor — a drug that reduces gastric acid secretion by blocking the proton pump within the oxyntic cells. Proton pump inhibitors include lansoprazole, omeprazole, and pantoprazole; they are used for treating gastric and duodenal ulcers, reflux… … Medical dictionary
proton-pump inhibitor — a drug that reduces gastric acid secretion by blocking the proton pump within the oxyntic (parietal) cells. Proton pump inhibitors include esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole; they are used for treating gastric… … The new mediacal dictionary
Discovery and development of proton pump inhibitors — Proton pump inhibitors (PPIs) block the gastric Hydrogen potassium ATPase (H+,K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid related diseases, including gastroesophageal reflux disease… … Wikipedia
proton pump — the enzyme in the oxyntic (parietal) cells of the stomach that causes acid secretion by producing hydrogen ions in exchange for potassium ions … The new mediacal dictionary
proton pump inhibitor — noun Date: 1983 any of a group of drugs that inhibit the activity of pumps transporting hydrogen ions across cell membranes and are used to inhibit gastric acid secretion … New Collegiate Dictionary
