isoprostane

isoprostane
Any of various prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidation of essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase enzyme.

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  • Isoprostane — The isoprostanes are prostaglandin like compounds formed in vivo from the free radical catalyzed peroxidationof essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase (COX) enzyme. [COX activity produces… …   Wikipedia

  • isoprostane — iso·pros·tane (i″so prosґtān) any of a group of prostaglandin isomers found in plasma and urine; some are increased in various pathological states …   Medical dictionary

  • Isofuran — Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted… …   Wikipedia

  • Essential fatty acid — Essential fatty acids, or EFAs, are fatty acids that cannot be constructed within an organism from other components (generally all references are to humans) by any known chemical pathways; and therefore mustbe obtained from the diet. The term… …   Wikipedia

  • Eicosanoid — In biochemistry, eicosanoids are signaling molecules made by oxygenation of twenty carbon essential fatty acids, (EFAs).They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central… …   Wikipedia

  • Thromboxane receptor — The thromboxane receptor is a protein on the surface of cells in the endothelium of blood vessels and in the placenta which interacts with the eicosanoid lipid thromboxane. It is a G protein coupled receptors coupled to the G protein Gq.cite… …   Wikipedia

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  • Prostaglandin F receptor — (FP) is a receptor for Prostaglandin F2α. It is encoded by the gene PTGFR.cite web | title = Entrez Gene: PTGFR prostaglandin F receptor (FP)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5737| accessdate …   Wikipedia

  • GNA11 — Guanine nucleotide binding protein (G protein), alpha 11 (Gq class), also known as GNA11, is a human gene.cite web | title = Entrez Gene: GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)| url =… …   Wikipedia

  • Alp Ikizler — T. Alp Ikizler is a nephrologist, currently holding the Catherine McLaughlin Hakim chair in Medicine at Vanderbilt University School of Medicine, where he does clinical work and heads a research lab. [… …   Wikipedia

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