thapsigargin

thapsigargin
A sesquiterpene lactone that is an inhibitor of a certain class of enzymes

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  • Thapsigargin — Chembox new Name = Thapsigargin ImageFile = Thapsigargin.png ImageName = Thapsigargin Section1 = Chembox Identifiers CASNo = 67526 95 8 Section2 = Chembox Properties Formula = C34H50O12 MolarMass = 650.76 g/mol Thapsigargin is a tight binding… …   Wikipedia

  • thapsigargin — Cell permeable inhibitor of calcium ATPase of endoplasmic reticulum; leads to increase in cytoplasmic calcium ions. Acts independently of InsP3. A tumour promoter …   Dictionary of molecular biology

  • trp — (1) Tryptophan. (2) Operon encoding tryptophan metabolism genes in E. coli. (3) Transient receptor potential mutant in Drosophila, gene codes for a constitutively active calcium permeable channel activated by thapsigargin(though trp1 is… …   Dictionary of molecular biology

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  • Bortezomib — Drugbox IUPAC name = [(1 R ) 3 methyl 1 [(2 S ) 1 oxo 3 phenyl 2 [(pyrazinylcarbonyl)amino] propyl] amino] butyl] boronic acid CAS number = 179324 69 7 ATC prefix = L01 ATC suffix = XX32 PubChem = 93860 DrugBank = APRD00828 C=19 | H=25 | B=1 |… …   Wikipedia

  • Insect diuretic hormones — are hormones that regulate water balance through diuretic action.The insect excretory system, responsible for regulating water balance in the insect, comprises the Malpighian tubules and the hindgut (the ileum and rectum). Malpighian tubules… …   Wikipedia

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  • Grob fragmentation — A Grob fragmentation, named for the British chemist Cyril A. Grob, is an elimination reaction taking place when an electrofuge and nucleofuge are situated in positions 1 and 3 on an aliphatic chain. [Grob, C. A.; Baumann, W. Helv. Chim. Acta 1955 …   Wikipedia

  • Osmotic shock — or osmotic stress is a sudden change in the solute concentration around a cell, causing a rapid change in the movement of water across its cell membrane. Under conditions of high concentrations of either salts, substrates or any solute in the… …   Wikipedia

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