milrinone

milrinone
An inhibitor of phosphodiesterase III that potentiates the effect of cyclic adenosine monophosphate.

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  • Milrinone — Systematic (IUPAC) name 2 methyl 6 oxo 1,6 dihydro 3,4 bipyridine 5 carbonitrile Clinical data AHFS/Drugs.com …   Wikipedia

  • Milrinone — МИЛРИНОН ( Milrinonе )*. 1,6 Дигидро 2 метил 6 оксо[3,4 бипиридин] 5 карбонитрил. Выпускается в виде лактата. Синоним: Рrimacor . По структуре и действию близок к амринону. Вместо аминогруппы содержит группу СN и имеет дополнительный метильный… …   Словарь медицинских препаратов

  • milrinone — A xanthine oxidase inhibitor which increases the force of contraction of the heart; used in congestive heart failure; resembles amrinone; cardiotonic. * * * mil·ri·none mil rə .nōn …   Medical dictionary

  • PDE3 inhibitor — Milrinone, one of the first PDE3 inhibitors used clinically A PDE3 inhibitor is a drug which inhibits the action of the phosphodiesterase enzyme PDE3. They are used for the therapy of acute heart failure and cardiogenic shock. Approved PDE3… …   Wikipedia

  • Amrinone — Systematic (IUPAC) name 5 amino 3,4 bipyridin 6(1H) one Clinical data AHFS/Drugs.com …   Wikipedia

  • Management of heart failure — requires a muitimodal approach. It involves a combination of lifestyle modifications, medications, and possibly the use of devices or surgery. Contents 1 Diet and lifestyle measures 1.1 Fluid restriction 2 Pharmacological management …   Wikipedia

  • Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… …   Wikipedia

  • Heart failure — Classification and external resources The major signs and symptoms of heart failure. ICD 10 I5 …   Wikipedia

  • Inotrope — An inotrope (pronEng|ˈaɪnətroʊp) is an agent that alters the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular… …   Wikipedia

  • Bipyridine — Bipyridines are a family of chemical compounds with the formula (C5H4N)2, which are formed by the coupling of two pyridine rings. Six isomers of bipyridine exist, but two isomers are prominent: 2,2 bipyridine is a popular ligand in coordination… …   Wikipedia

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