dihydrofolate
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Dihydrofolate — Vitamine B9 Vitamine B9 Structure chimique de la vitamine B9 Général Synonymes acide folique vitamine M fola … Wikipédia en Français
Dihydrofolate reductase — Ribbon diagram of human dihydrofolate reductase in complex with folate (blue). From PDB 1DRF … Wikipedia
Dihydrofolate synthase — Identifiers EC number 6.3.2.12 CAS number 37318 62 0 … Wikipedia
Dihydrofolate réductase — Structure de la DHFR complexée au folate (à gauche) et au NADPH (à droite) … Wikipédia en Français
dihydrofolate reductase — dihydrofolate reductase. См. дигидрофолатредуктаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Dihydrofolate reductase inhibitor — A dihydrofolate reductase inhibitor is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate. Since folate is needed by rapidly dividing cells to make thymine, this effect may be used to therapeutic… … Wikipedia
dihydrofolate reductase — An enzyme reversibly oxidizing tetrahydrofolate to 7,8 dihydrofolate with NADP+. A crucial enzyme in one carbon metabolism; used as a marker of drug resistance to methotrexate. SYN: 5,6,7,8 tetrahydrofolate dehydrogenase. * * * di·hy·dro·fo·late… … Medical dictionary
dihydrofolate reductase — (= DHFR) An enzyme (EC 1.5.1.3) involved in the biosynthesis of folic acid coenzymes, that transfers hydrogen from NADP to dihydrofolate, yielding tetrahydrofolic acid, an essential vitamin cofactor in purine, thymidine and methionine synthesis.… … Dictionary of molecular biology
dihydrofolate — di·hy·dro·fo·late (DHF) (di hi″dro foґlāt) an ester or dissociated form of dihydrofolic acid … Medical dictionary
dihydrofolate reductase inhibitor — any of various drugs that interfere with the conversion of folic acid to its active form in the body. They include pyrimethamine, trimethoprim, triamterene, and methotrexate. When such drugs are necessary, folate deficiency is treated with… … Medical dictionary
