phosphoramidite

phosphoramidite
Any of a class of organic compounds formally derived from a phosphite by replacing a >P-O-R with a >P-N<R group; used in the synthesis of nucleic acids etc

The resultant phosphoramidite is stable and can be stored in the absence of moisture as a white powder.


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  • Phosphoramidite — Nucleoside phosphoramidites are used to synthesise short nucleic acid chains.The chemical process allows several modifications, such as linker arms or using alternative nucleotides, such as LNA or morpholino or 2 group modified (OMe, NH2, F) or… …   Wikipedia

  • phosphoramidite — Nucleotide derivative used in oligonucleotide synthesis …   Dictionary of molecular biology

  • Nucleoside phosphoramidite — Protected 2 deoxynucleoside phosphoramidites. Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides. They are used to synthesize oligonucleotides, relatively short fragments of nucleic acid and their analogs. Nucleoside… …   Wikipedia

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  • Síntesis de oligonucleótidos — La síntesis de oligonucleótidos es la síntesis química de fragmentos relativamente cortos de ácido nucleico con una secuencia estructural química definida. La técnica es extremadamente útil en la práctica actual en laboratorios, porque provee un… …   Wikipedia Español

  • Organophosphorus — compounds are degradable organic compounds containing carbon–phosphorus bonds (thus excluding from phosphate and phosphite esters, which lack such kind of bonding), used primarily in pest control as an alternative to chlorinated hydrocarbons that …   Wikipedia

  • Nucleic acid analogues — Not to be confused with degenerate bases. For phosphoramidite synthesis of nucleic acids, see Oligonucleotide synthesis. RNA with its nucleobases to the left and DNA to the right. Nucleic acid analogues are compounds structurally similar (analog) …   Wikipedia

  • Thiophosphate — For the thiophosphate esters see organothiophosphates. A thiophosphate (or phosphorothioate) is a family of compounds and anions with the general chemical formula PS4 xOx3 (x = 0, 1, 2, or 3). The state of protonation is usually not specified.… …   Wikipedia

  • Synthèse d'oligonucléotide — La synthèse d oligonucléotide est la synthèse chimique de fragments relativement courts d acide nucléique avec une structure définie. Sommaire 1 Principe 2 Histoire 2.1 Synthèse à l aide de phosphodiester …   Wikipédia en Français

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